Prediction of the Mechanical Response of Trabecular Bone during Press-Fit Fixation of A Total Joint Replacement
Prediction of trabecular bone's biomechanical (biological and mechanical) behavior has long eluded researchers and orthopaedic specialists in part due to bone's non-homogeneity and its anisotropic, nonlinear biomechanical behavior. Although many micro finite element (μFE) models have been developed to simulate trabecular bone geometry and mechanical behavior, none are used to predict remodeling. The biomechanical behavior of bone is especially important when considering methods for promoting bone health throughout the aging process, preventing fractures, and improving surgical procedures and devices used for total joint replacement (TJR).
The goal of this research is to ultimately develop a computational model for predicting trabecular bone remodeling. The biomechanical response of trabecular bone will first be characterized experimentally using a combination of mechanical and imaging methods. These results will then be implemented in a µFE model that is capable of predicting the remodeling response of trabecular bone. A computational model that simulates trabecular bone would greatly augment the understanding of its biomechanical behavior and lead to improved osteoporosis treatment methods, joint implant designs, and surgical procedures that are dependent on patient-specific information.
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